Systemic \Sys*tem"ic\, a. 1. Of or relating to a system; common to a system; as, the systemic circulation of the blood. 2. (Anat. & Physiol.) Of or pertaining to the general system, or the body as a whole; as, systemic death, in distinction from local death; systemic circulation, in distinction from pulmonic circulation; systemic diseases. {Systemic death}. See the Note under {Death}, n., 1.