Podophyllum \Pod`o*phyl"lum\, n. [NL., fr. Gr. poy`s, podo`s, foot + ? leaf.] 1. (Bot.) A genus of herbs of the Barberry family, having large palmately lobed peltate leaves and solitary flower. There are two species, the American {Podohyllum peltatum}, or May apple, the Himalayan {P. Emodi}. 2. (Med.) The rhizome and rootlet of the May apple ({Podophyllum peltatum}), -- used as a cathartic drug.