Mestizo \Mes*ti"zo\, n.; pl. {Mestizos}. [Sp. mestizo; akin to OF. mestis, F. m['e]tis; all fr. (assumed) LL. mixtitius, fr. L. mixtus mixed, p. p. of miscere to mix. See {Mix}, and cf. {Mestee}, {M['E]tif}, {M['E]tis}, {Mustee}.] The offspring of an Indian or a negro and a European or person of European stock. [Spanish America] {Mestizo wool}, wool imported from South America, and produced by mixed breeds of sheep.