Manacle \Man"a*cle\, v. t. [imp. & p. p. {Manacled}; p. pr. & vb. n. {Manacling}.] To put handcuffs or other fastening upon, for confining the hands; to shackle; to confine; to restrain from the use of the limbs or natural powers. Is it thus you use this monarch, to manacle and shackle him hand and foot ? --Arbuthnot.