Lethargize \Leth"ar*gize\ (l[e^]th"[.a]r*j[imac]z), v. t. [imp. & p. p. {Lethargized} (-j[imac]zd); p. pr. & vb. n. {Lethargizing} (-j[imac]`z[i^]ng).] To make lethargic. All bitters are poison, and act by stilling, and depressing, and lethargizing the irritability. --Coleridge.