Fatigue \Fa*tigue"\, v. t. [imp. & p. p. {Fatigued}; p. pr. & vb. n. {Fatiguing}, n.] [Cf. F. fatiguer. See {Fatigue}, n.] To weary with labor or any bodily or mental exertion; to harass with toil; to exhaust the strength or endurance of; to tire. Syn: To jade; tire; weary; bore. See {Jade}.